Categories: Drugs information

Generic Name: Nifedipine
Brand Names: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL

Dosage Form: tablet, film coated for oral use

Adalat is a pill dosage form of the calcium channel blocker nifedipine, which is 3.5 pyridinedicarboxylic acid. Nifedipine relaxes your blood vessels providing easier blood flow from the heart and reducing its workload. Adalat is mainly used to treat hypertension and angina (chest pain). The mechanism of action of the drug involves reducing arterial blood pressure by peripheral arterial vasodilatation and reducing in peripheral vascular risistance. Nifedipine is a peripheral arterial vasodilator working on vascular smooth muscle and reducing arterial blood pressure.

Before using this drug consult your doctor. You may need to undergo special tests before your doctor will direct you exact dose.

Do not use Adalat if you are allergic to nifedipine or if you have any of these health conditions:

  • kidney disease or liver disease (especially cirrhosis);
  • coronary artery disease;
  • congestive heart failure;
  • digestive problems.

Many drugs can interact with Adalat. Inform your doctor about all other drugs you use, especially:

  • acarbose (Precose);
  • cimetidine (Tagamet);
  • fentanyl (Actiq, Duragesic, Fentora) or other narcotic pain medications;
  • digoxin (Lanoxin);
  • nefazodone;
  • St. John’s wort;
  • rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate) or rifapentine (Priftin);
  • a blood thinner such as warfarin (Coumadin);
  • an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), or erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin);
  • antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);
  • a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren), and others;
  • a heart rhythm medication such as quinidine (Quin-G) or flecaininde (Tambocor);
  • HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), or ritonavir (Norvir, Kaletra, or saquinavir (Invirase);
  • medicines used to prevent organ transplant rejection, such as sirolimus (Rapamune) or tacrolimus (Prograf);
  • other heart or blood pressure medications such as benazepril (Lotensin), diltiazem (Cartia, Cardizem), doxazosin (Cardura), or verapamil (Calan, Covera, Isoptin, Verelan); or
  • seizure medication such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Solfoton), or phenytoin (Dilantin).
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Grapefruit and grapefruit juice may lead to potentially dangerous effects of the drug.

Do not get up too fast from a sitting or lying position, to avoid dizziness. Get up slowly and steady yourself to prevent a fall.

Do not drink alcohol while taking this drug; alcohol can lower your blood pressure may increase certain side effects of Adalat.

Take Adalat according to your doctor’s prescriptions; do not stop taking it without first talking to your doctor. If you stop suddenly your condition may get worse. Do not take the drug in larger or smaller doses, take the exact dose your doctor directed to you.

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Take the drug on an empty stomach. Do not crush, chew, or break the tablet. Swallow it whole.

You may need to check blood pressure often and you may need to make blood tests regularly.

Adalat serious side effects include:

  • worsening angina;
  • shortage of breath, swelling in your hands or feet;
  • fast or pounding heartbeats;
  • numbness or tingly feeling;
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.

Serious side effects occur rarely, still if you experience any of these conditions, get emergency medical help.

Less serious Adalat side effects include:

  • headache;
  • drowsiness, tired feeling;
  • nausea, diarrhea, stomach pain;
  • insomnia;
  • mild rash or itching;
  • joint pain;
  • urinating more than usual.

Store this drug at room temperature away from moisture and heat.

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